Audiologic monitoring of multi-drug resistant tuberculosis patients on aminoglycoside treatment with long term follow-up.

摘要: Multi-drug resistant tuberculosis has emerged as a significant problem with the resurfacing of and thus need to use second line drugs resultant increased incidence adverse effects. We discuss effect aminoglycoside anti-tubercular on hearing status MDR-TB patients. Sixty four patients were put anti-TB drugs. These divided into three groups: group I, 34 using amikacin, II, 26 kanamycin III, 4 capreomycin. Of these, 18.75% developed sensorineural loss involving higher frequencies while 6.25% had involvement speech also. All seen again approximately one year after discontinuation all losses permanent no threshold improvement. Aminoglycosides used in may result irreversible can become handicap are also involved some underlining for regular audiologic evaluation during treatment.