Immune response to inspiratory muscle training in patients with chronic heart failure.

摘要: BackgroundThe effects of inspiratory muscle training on plasma cytokines, C-reactive protein and the soluble apoptosis mediators Fas ligand in chronic heart failure are unknown.Design methodsThirty-eight patients with failure, age 57 ± 2 years, New York Heart Association classification II-III, were assigned to either a high intensity group (n = 15, 53±2 years) exercised at 60% sustained maximal pressure, or low 23, 59 years), 15% three times per week for 10 weeks. Patients matched age, sex functional class. Plasma levels tumor necrosis factor (TNF)-α, TNF receptor I, interleukin-6, protein, measured baseline post-inspiratory training. Pulmonary function was ass...