Extraversion modulates functional connectivity hubs of resting-state brain networks

摘要: Personality dimension extraversion describes individual differences in social behaviour and socio-emotional functioning. The intrinsic functional connectivity patterns of the brain are reportedly associated with extraversion. However, whether or not is hubs warrants clarification. Functional involved rapid integration neural processing, their dysfunction contributes to development neuropsychiatric disorders. In this study, we employed density (FCD) method for first time distinguish energy-efficient resting-state magnetic resonance imaging data 71 healthy subjects were used analysis. Short-range FCD was positively correlated left cuneus, revealing a link between local activity region risk-taking. Long-range negatively right superior frontal gyrus inferior gyrus. Seed-based (RSFC) analyses revealed that decreased long-range individuals high scores showed low pattern medial dorsolateral prefrontal cortex, middle temporal gyrus, anterior cingulate cortex. This result suggests RSFC responsible self-esteem, self-evaluation, inhibitory system account modulation shaping Overall, our results emphasize specific hubs, reveal connections relation extraversion, thereby providing neurobiological basis