Freeze-all policy: fresh vs. frozen-thawed embryo transfer
作者： Matheus Roque , Marcello Valle , Fernando Guimarães , Marcos Sampaio , Selmo Geber
DOI: 10.1016/J.FERTNSTERT.2015.01.045
关键词:
摘要: Objective To compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET (the "freeze-all" policy), with performed only in cases without progesterone (P) elevation. Design Prospective, observational, cohort study. Setting Private IVF center. Patient(s) A total of 530 patients submitted to controlled ovarian stimulation (COS) a gonadotropin-releasing hormone–antagonist protocol, cleavage-stage, day-3 ET. Intervention(s) None. Main Outcome Measure(s) Ongoing pregnancy rates. Result(s) cycles were included the analysis: 351 group (when P levels ≤1.5 ng/mL on trigger day); 179 freeze-all (ET after endometrial priming estradiol valerate, at 6 mg/d, taken orally). For vs. group, respectively, implantation rate was 19.9% 26.5%; clinical 35.9% 46.4%; ongoing 31.1% 39.7%. Conclusion(s) The significantly better using policy, compared ET. These results suggest that even select underwent (P ≤1.5 ng/mL), receptivity may have been impaired by COS, be improved policy.
fertstert.org
elsevier.com
sci-hub.se 参考文章(25)
Rachel Weinerman, Monica Mainigi, Why we should transfer frozen instead of fresh embryos: the translational rationale Fertility and Sterility. ,vol. 102, pp. 10- 18 ,(2014) , 10.1016/J.FERTNSTERT.2014.05.019
Selmo Geber, Ana Carolina Ferreira Moreira, Sálua Oliveira Calil de Paula, Marcos Sampaio, Comparison between two forms of vaginally administered progesterone for luteal phase support in assisted reproduction cycles Reproductive Biomedicine Online. ,vol. 14, pp. 155- 158 ,(2007) , 10.1016/S1472-6483(10)60782-1
Ana Cobo, María José de los Santos, Damià Castellò, Pilar Gámiz, Pilar Campos, José Remohí, Outcomes of vitrified early cleavage-stage and blastocyst-stage embryos in a cryopreservation program: evaluation of 3,150 warming cycles Fertility and Sterility. ,vol. 98, pp. 1138- 1146 ,(2012) , 10.1016/J.FERTNSTERT.2012.07.1107
Mary Ellen Pavone, Joy Innes, Jennifer Hirshfeld-Cytron, Ralph Kazer, John Zhang, None, Comparing thaw survival, implantation and live birth rates from cryopreserved zygotes, embryos and blastocysts Journal of Human Reproductive Sciences. ,vol. 4, pp. 23- 28 ,(2011) , 10.4103/0974-1208.82356
S. Santos-Ribeiro, N.P. Polyzos, P. Haentjens, J. Smitz, M. Camus, H. Tournaye, C. Blockeel, Live birth rates after IVF are reduced by both low and high progesterone levels on the day of human chorionic gonadotrophin administration Human Reproduction. ,vol. 29, pp. 1698- 1705 ,(2014) , 10.1093/HUMREP/DEU151
Georg Griesinger, Bernadette Mannaerts, Claus Yding Andersen, Han Witjes, Efstratios M. Kolibianakis, Keith Gordon, Progesterone elevation does not compromise pregnancy rates in high responders: a pooled analysis of in vitro fertilization patients treated with recombinant follicle-stimulating hormone/gonadotropin-releasing hormone antagonist in six trials Fertility and Sterility. ,vol. 100, pp. 1622- 1628.e3 ,(2013) , 10.1016/J.FERTNSTERT.2013.08.045
Bruce S. Shapiro, Said T. Daneshmand, Forest C. Garner, Martha Aguirre, Cynthia Hudson, Clinical rationale for cryopreservation of entire embryo cohorts in lieu of fresh transfer. Fertility and Sterility. ,vol. 102, pp. 3- 9 ,(2014) , 10.1016/J.FERTNSTERT.2014.04.018
Selmo Geber, Liana Sales, Marcos AC Sampaio, Laboratory techniques for human embryos. Reproductive Biomedicine Online. ,vol. 5, pp. 211- 218 ,(2002) , 10.1016/S1472-6483(10)61625-2
Patricia Díaz-Gimeno, José A. Horcajadas, José A. Martínez-Conejero, Francisco J. Esteban, Pilar Alamá, Antonio Pellicer, Carlos Simón, A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature Fertility and Sterility. ,vol. 95, pp. 50- 60 ,(2011) , 10.1016/J.FERTNSTERT.2010.04.063
Leyre Herrero, Mónica Martínez, Juan A Garcia-Velasco, Current status of human oocyte and embryo cryopreservation. Current Opinion in Obstetrics & Gynecology. ,vol. 23, pp. 245- 250 ,(2011) , 10.1097/GCO.0B013E32834874E2