Effects of cytochrome P450 3A4 and non-genetic factors on initial voriconazole serum trough concentrations in hematological patients with different cytochrome P450 2C19 genotypes.

作者: Beibei Shao , Yongcheng Ma , Qiaoyan Li , Yimeng Wang , Zunmin Zhu

DOI: 10.1080/00498254.2016.1271960

关键词:

摘要: Abstract1. Polymorphisms of cytochrome P450 2C19 (CYP2C19) is an important factor contributing to variability voriconazole pharmacokinetics. Polymorphisms CYP3A4, CYP3A5, CYP2C9 and non-genet...

参考文章(42)
Tian Ye, Ran Tong, Zhiqiang Gao, Genotyping of Single Nucleotide Polymorphisms Springer, Cham. pp. 123- 144 ,(2015) , 10.1007/978-3-319-17305-4_6
Joachim D. Weigel, Nicole G. M. Hunfeld, Birgit C. P. Koch, Mohamud Egal, Jan Bakker, Ron H. N. van Schaik, Teun van Gelder, Gain-of-function single nucleotide variants of the CYP2C19 gene (CYP2C19*17) can identify subtherapeutic voriconazole concentrations in critically ill patients: a case series. Intensive Care Medicine. ,vol. 41, pp. 2013- 2014 ,(2015) , 10.1007/S00134-015-4002-Z
WW Hope, E Castagnola, AH Groll, E Roilides, M Akova, MC Arendrup, SEVTAP Arikan‐Akdagli, Matteo Bassetti, J Bille, OA Cornely, M Cuenca‐Estrella, J Peter Donnelly, J Garbino, R Herbrecht, HE Jensen, BJ Kullberg, C Lass‐Flörl, O Lortholary, Wouter Meersseman, G Petrikkos, MD Richardson, PE Verweij, C Viscoli, AJ Ullmann, ESCMID Fungal Infection Study Group (EFISG), ESCMID* guideline for the diagnosis and management of Candida diseases 2012: prevention and management of invasive infections in neonates and children caused by Candida spp Clinical Microbiology and Infection. ,vol. 18, pp. 38- 52 ,(2012) , 10.1111/1469-0691.12040
O Lortholary, G Petrikkos, M Akova, MC Arendrup, SEVTAP Arikan‐Akdagli, Matteo Bassetti, J Bille, T Calandra, E Castagnola, OA Cornely, M Cuenca‐Estrella, JP Donnelly, J Garbino, AH Groll, R Herbrecht, WW Hope, HE Jensen, BJ Kullberg, C Lass‐Flörl, Wouter Meersseman, MD Richardson, E Roilides, PE Verweij, C Viscoli, AJ Ullmann, ESCMID Fungal Infection Study Group (EFISG), ESCMID* guideline for the diagnosis and management of Candida diseases 2012: patients with HIV infection or AIDS Clinical Microbiology and Infection. ,vol. 18, pp. 68- 77 ,(2012) , 10.1111/1469-0691.12042
S. Miyakis, S.J. van Hal, J. Ray, D. Marriott, Voriconazole concentrations and outcome of invasive fungal infections Clinical Microbiology and Infection. ,vol. 16, pp. 927- 933 ,(2010) , 10.1111/J.1469-0691.2009.02990.X
Tess V. Clendenen, Justin Rendleman, Wenzhen Ge, Karen L. Koenig, Isaac Wirgin, Diane Currie, Roy E. Shore, Tomas Kirchhoff, Anne Zeleniuch-Jacquotte, Genotyping of Single Nucleotide Polymorphisms in DNA Isolated from Serum Using Sequenom MassARRAY Technology PLOS ONE. ,vol. 10, pp. e0135943- ,(2015) , 10.1371/JOURNAL.PONE.0135943
L. Purkins, N. Wood, P. Ghahramani, K. Greenhalgh, M. J. Allen, D. Kleinermans, Pharmacokinetics and Safety of Voriconazole following Intravenous- to Oral-Dose Escalation Regimens Antimicrobial Agents and Chemotherapy. ,vol. 46, pp. 2546- 2553 ,(2002) , 10.1128/AAC.46.8.2546-2553.2002
Lingling Chen, Shengying Qin, Jing Xie, Jimin Tang, Lun Yang, Wen Shen, Xinzhi Zhao, Jing Du, Guang He, Guoyin Feng, Lin He, Qinghe Xing, Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China Pharmacogenomics. ,vol. 9, pp. 691- 702 ,(2008) , 10.2217/14622416.9.6.691
Yukihiro Hamada, Yoshinori Seto, Kazuo Yago, Masakazu Kuroyama, Investigation and threshold of optimum blood concentration of voriconazole: a descriptive statistical meta-analysis Journal of Infection and Chemotherapy. ,vol. 18, pp. 501- 507 ,(2012) , 10.1007/S10156-011-0363-6
Norie Murayama, Naoko Imai, Takahisa Nakane, Makiko Shimizu, Hiroshi Yamazaki, Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes Biochemical Pharmacology. ,vol. 73, pp. 2020- 2026 ,(2007) , 10.1016/J.BCP.2007.03.012