Cerebellar Timing Systems

摘要: Coordinated movement requires the normal operation of a number different brain structures. Taking modular perspective, it is argued that these structures provide unique computations in concert produce coordinated behavior. The coordination problems patients with cerebellar lesions can be understood as problem controlling and regulating temporal patterns movement. timing capabilities cerebellum are not limited to motor domain, but utilized perceptual tasks require precise representation information. Patients impaired judging duration short auditory stimulus or velocity moving visual stimulus. hypothesis also provides computational account role certain types learning. In particular, essential for situations which animal must learn relationship between successive events such eyeblink conditioning. Modeling behavioral studies suggest system best characterized providing near-infinite set interval type timers rather than single clock pacemaker oscillatory properties. Thus, will invoked whenever task its function, exact neural elements activated vary from task. multiple-timer suggests an alternative neuroimaging results implicating higher cognitive processes. activation may reflect automatic preparation multiple responses associated processes semantic analysis, error detection, attention shifting, response selection.