Minimally invasive techniques in breast cancer treatment.

摘要: Breast conservation therapy has largely replaced mastectomy as the surgical treatment of choice for early-stage breast cancer. As sentinel lymph node mapping procedure, rather than routine axillary dissection, becomes standard care, next challenge is how to treat primary tumor without surgery. Minimally invasive ablation possible with a variety approaches; goal either excise percutaneously or cool it (with cryotherapy) heat radiofrequency (RFA), focused ultrasound, laser interstitial therapy) sufficiently cause complete cell death. These developing technologies may provide options that are psychologically and cosmetically more acceptable patient traditional therapies, but they need further investigation prove oncologically sound. This new frontier surgery scalpels will require surgeons develop radiologic expertise acquire basic understanding molecular biology. Semin. Surg. Oncol. 20:246–250, 2001. © 2001 Wiley-Liss, Inc.