A global reference for fetal-weight and birthweight percentiles

摘要: Summary Background Definition of small for gestational age in various populations worldwide remains a challenge. References based on birthweight are deficient preterm births, those derived from ultrasound estimates might not be applicable to all populations, and the individualised reference can too complex use developing countries. Our aim was create generic fetal weight that overcame these deficiencies could readily adapted local populations. Methods We used fetal-weight developed by Hadlock colleagues notion proportionality proposed Gardosi made easily adjustable according mean at 40 weeks gestation any population. For application validation, we data 24 countries Africa, Latin America, Asia participated 2004–08 WHO Global Survey Maternal Perinatal Health (237 025 births). compared our with (non-customised) (individualised). every reference, odds ratio (OR) adverse perinatal outcomes (stillbirths, neonatal deaths, referral higher-level or special care unit, Apgar score lower than 7 5 min) infants who were versus estimated multilevel logistic regression. Findings OR 1·59 (95% CI 1·53–1·66) non-customised 2·87 (2·73–3·01) country-specific 2·84 (2·71–2·99) fully reference. Interpretation percentiles It has better ability predict is simpler without loss predictive ability. Funding None.