A molecular assembly that crawls on a solid substrate with a metabolic-like process

作者: Masato Nakada , Yukihiro Fujikami , Masaharu Kawaguchi , Daigo Yamamoto , Akihisa Shioi

DOI: 10.1039/C5ME00012B

关键词:

摘要: A vesicular aggregate filled with lipid molecules exhibited crawling motion over a glass surface as result of chemical reactions. The was composed didodecyldimethylammonium bromide (DDAB) and sodium oleate calcium ions. induced by the reaction between DDAB iodide ions, it caused discharge inner lipids. This responsible for size reduction aggregate. However, engulfed neighboring smaller vesicles, which were taken up into in dehydrated state became constituent recovered could translate sustainable manner. is probably first example an amphiphilic molecular assembly that exhibits reactions without reduction. may be regarded cell-like behavior abiotic metabolic-like process.

参考文章(81)
Galina G Hovhannisyan, Rouben M Arutyunyan, Tigran S Haroutunyan, Evaluation of cisplatin-DNA crosslinks formation with UV-C application by the alkaline Comet-assay Experimental Oncology. ,vol. 26, pp. 240- 242 ,(2004)
Mauro Ravera, Elisabetta Gabano, Ilaria Zanellato, Ilaria Bonarrigo, Manuela Alessio, Fabio Arnesano, Angela Galliani, Giovanni Natile, Domenico Osella, Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs. Journal of Inorganic Biochemistry. ,vol. 150, pp. 1- 8 ,(2015) , 10.1016/J.JINORGBIO.2015.05.012
Erika Nawa, Daigo Yamamoto, Akihisa Shioi, Chemotactic Amoeboid-Like Shape Change of a Vesicle under a pH Gradient Bulletin of the Chemical Society of Japan. ,vol. 88, pp. 1536- 1544 ,(2015) , 10.1246/BCSJ.20150190
M. Corte-Rodríguez, M. Espina, L.M. Sierra, E. Blanco, T. Ames, M. Montes-Bayón, A. Sanz-Medel, Quantitative evaluation of cellular uptake, DNA incorporation and adduct formation in cisplatin sensitive and resistant cell lines: Comparison of different Pt-containing drugs. Biochemical Pharmacology. ,vol. 98, pp. 69- 77 ,(2015) , 10.1016/J.BCP.2015.08.112
Wilma M. McKoy, Karen R. Grotzinger, Karen G. Louie, Robert F. Ozols, Turid Knutsen, Robert C. Young, Brent C. Behrens, Brent C. Behrens, Jacqueline Whang-Peng, Thomas C. Hamilton, Hidetaka Masuda, Characterization of a cis-Diamminedichloroplatinum(II)-resistant Human Ovarian Cancer Cell Line and Its Use in Evaluation of Platinum Analogues Cancer Research. ,vol. 47, pp. 414- 418 ,(1987)
Akshada Sawant, Anbarasi Kothandapani, Anatoly Zhitkovich, Robert W. Sobol, Steve M. Patrick, Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links. DNA Repair. ,vol. 35, pp. 126- 136 ,(2015) , 10.1016/J.DNAREP.2015.10.003
Gerd Bendas, Hans-Dieter Royer, Martin Koch, Daniel Philipp Stölting, Michael Wiese, Michaela Borrmann, How liposomal Cisplatin overcomes chemoresistance in ovarian tumour cells. Anticancer Research. ,vol. 34, pp. 525- 530 ,(2014)
D. Yamamoto, T. Takada, M. Tachibana, Y. Iijima, A. Shioi, K. Yoshikawa, Micromotors working in water through artificial aerobic metabolism Nanoscale. ,vol. 7, pp. 13186- 13190 ,(2015) , 10.1039/C5NR03300D
Jochen Zisowsky, Susanne Koegel, Stefan Leyers, Krishna Devarakonda, Matthias U. Kassack, Maja Osmak, Ulrich Jaehde, Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells Biochemical Pharmacology. ,vol. 73, pp. 298- 307 ,(2007) , 10.1016/J.BCP.2006.10.003
E. Kaler, A. Murthy, B. Rodriguez, J. Zasadzinski, Spontaneous vesicle formation in aqueous mixtures of single-tailed surfactants Science. ,vol. 245, pp. 1371- 1374 ,(1989) , 10.1126/SCIENCE.2781283