Molecular epidemiology of cystic echinococcosis.

摘要: Echinococcus granulosus exhibits substantial genetic diversity that has important implications for the design and development of vaccines, diagnostic reagents drugs effective against this parasite. DNA approaches have been used accurate identification these variants are presented here as is a description their application in molecular epidemiological surveys cystic echinococcosis different geographical settings host assemblages. The recent publication complete sequences mitochondrial (mt) genomes horse sheep strains E. multilocularis, availability mt number other genotypes, provided additional information can be more depth strain characterization taxonomic studies parasites. This very rich sequence solid basis, along with range biological, epidemiological, biochemical molecular-genetic criteria, revising taxonomy genus Echinococcus. controversial issue some time. Furthermore, accumulating data may allow insight to several unresolved questions such confirming occurrence precise nature G9 genotype its reservoir Poland, whether it present elsewhere, why camel (G6 genotype) appears affect humans certain areas but not others, delineation geographic ranges genotypes characterised date, remain identified.