Peripheral vestibular loss detected in pediatric patients using a smartphone-based test of the subjective visual vertical

作者: Jacob R. Brodsky , Brandon A. Cusick , Kosuke Kawai , Margaret Kenna , Guangwei Zhou

DOI: 10.1016/J.IJPORL.2015.09.020

关键词:

摘要: Abstract Introduction Detection of peripheral vestibular loss (PVL) in children with dizziness is an important and challenging task. The static subjective visual vertical (SVV) test can effectively detect PVL, but requires specialized equipment. Objective goal this study was to determine the efficacy a smartphone-based SVV at detecting PVL pediatric patients. Methods Thirty-nine patients between 7 18 years old (mean = 14.0 ± 2.70) underwent conventional (conv-SVV) (ip-SVV) testing. Subjects included 6 (based on clinical history other tests), benign paroxysmal positioning vertigo (BPPV), 11 central causes (CV), 8 non-vestibular (NVD), controls. Results Mean ip-SVV score group (2.77 ± 1.45) significantly higher than each groups (BPPV = 0.89 ± 0.55; CV = 1.08 ± 0.68; NVD = 1.45 ± 1.19; Control = 1.08 ± 0.73; one-way analysis variance, p  = 0.008), remained significant after adjusting for age gender by multiple linear regression analysis. Receiver operating characteristic predicted optimal cut-off >2.13° sensitivity 66.7%, specificity 97.0%, positive predictive value (PPV) 80%, negative 94.1% PVL. Sensitivity PPV improved 75% 100%, respectively, when subjects tested >1 month symptom onset ( n  = 24) were excluded. Conclusion Smartphone-based testing simple useful office-based method dizziness.

参考文章(28)
Safran Ab, Häusler R, Vibert D, Subjective visual vertical in peripheral unilateral vestibular diseases. Journal of Vestibular Research-equilibrium & Orientation. ,vol. 9, pp. 145- 152 ,(1999)
Yasuo Ogawa, Koji Otsuka, Shigetaka Shimizu, Taro Inagaki, Takahito Kondo, Mamoru Suzuki, Subjective visual vertical perception in patients with vestibular neuritis and sudden sensorineural hearing loss. Journal of Vestibular Research-equilibrium & Orientation. ,vol. 22, pp. 205- 211 ,(2012) , 10.3233/VES-2012-0447
Steven S. Hamilton, Guangwei Zhou, Jacob R. Brodsky, Video head impulse testing (VHIT) in the pediatric population International Journal of Pediatric Otorhinolaryngology. ,vol. 79, pp. 1283- 1287 ,(2015) , 10.1016/J.IJPORL.2015.05.033
F Mast, A Böhmer, Chronic unilateral loss of otolith function revealed by the subjective visual vertical during off center yaw rotation. Journal of Vestibular Research-equilibrium & Orientation. ,vol. 9, pp. 413- 422 ,(1999)
A H Clarke, K Helling, U Schönfeld, Unilateral examination of utricle and saccule function. Journal of Vestibular Research-equilibrium & Orientation. ,vol. 13, pp. 215- 225 ,(2003)
Andreas Böhmer, Fred Mast, Thomas Jarchow, Can a unilateral loss of otolithic function be clinically detected by assessment of the subjective visual vertical Brain Research Bulletin. ,vol. 40, pp. 423- 427 ,(1996) , 10.1016/0361-9230(96)00137-2
Seok Min Hong, Seung Geun Yeo, Jae Yong Byun, Moon Suh Park, Chan Hum Park, Jun Ho Lee, Subjective visual vertical during eccentric rotation in patients with vestibular neuritis. European Archives of Oto-rhino-laryngology. ,vol. 267, pp. 357- 361 ,(2010) , 10.1007/S00405-009-1064-Y
T.-H. Yang, S.-Y. Oh, K. Kwak, J.-M. Lee, B.-S. Shin, S.-K. Jeong, Topology of brainstem lesions associated with subjective visual vertical tilt Neurology. ,vol. 82, pp. 1968- 1975 ,(2014) , 10.1212/WNL.0000000000000480
Mario Faralli, Giampietro Ricci, Egisto Molini, Fabrizio Longari, Guido Altissimi, Antonio Frenguelli, Determining subjective visual vertical: dynamic versus static testing. Otology & Neurotology. ,vol. 28, pp. 1069- 1071 ,(2007) , 10.1097/MAO.0B013E31815AEA1B
Th. BRANDT, M. DIETERICH, Cyclorotation of the eyes and subjective visual vertical in vestibular brain stem lesions. Annals of the New York Academy of Sciences. ,vol. 656, pp. 537- 549 ,(1992) , 10.1111/J.1749-6632.1992.TB25234.X