Oral fluid, a substitute for serum to monitor measles IgG antibody?
作者： A Goyal , NJ Shaikh , AA Kinikar , NS Wairagkar
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摘要: We have analyzed the suitability and potential of Oral Fluid (OF) to substitute serum in estimating measles IgG antibodies, during community surveys, by comparing Optical Density (OD) antibodies OF 100 apparently asymptomatic children. antibody status was determined using commercially available - Measles Capture ELISA. Sensitivity 89.5%, specificity 90.6% Concordance 89%, coefficient correlation r is equal 0.97 (Karl Pearson's) rho 0.86 (Spearman's), found between OD value serum. The study emphasizes surrogate among collection advantageous over blood as it painless. It suitable for non-technical staff, easy transport less bio-hazardous.
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