PLANEJAMENTO, SÍNTESE E AVALIAÇÃO FARMACOLÓGICA DE COMPOSTOS HÍBRIDOS POTENCIALMENTE ATIVOS PARA O TRATAMENTO DA ANEMIA FALCIFORME

作者: Jean Leandro dos Santos

DOI:

关键词:

摘要: Universidade Estadual Paulista 'Julio de Mesquita Filho' - Unesp Faculdade Ciencias Farmaceuticas Departamento Farmacos e Medicamentos, Rodovia Araraquara-Jau Km.01 s/n Campus Universitario, 14801-902 Araraquara-SP

参考文章(77)
John W. Yarbro, Mechanism of action of hydroxyurea. Seminars in Oncology. ,vol. 19, pp. 1- 10 ,(1992) , 10.5555/URI:PII:009377549290123I
Michael Gütschow, Thomas Hecker, Andrea Thiele, Sunna Hauschildt, Kurt Eger, Aza analogues of thalidomide: synthesis and evaluation as inhibitors of tumor necrosis factor-alpha production in vitro. Bioorganic & Medicinal Chemistry. ,vol. 9, pp. 1059- 1065 ,(2001) , 10.1016/S0968-0896(00)00323-0
Valerie N. Hanft, Steven R. Fruchtman, Chrisley V. Pickens, Wendell F. Rosse, Thad A. Howard, Russell E. Ware, Acquired DNA mutations associated with in vivo hydroxyurea exposure. Blood. ,vol. 95, pp. 3589- 3593 ,(2000) , 10.1182/BLOOD.V95.11.3589
Mabel Koshy, Louise Dorn, Linda Bressler, Robert Molokie, Donald Lavelle, Nasrin Talischy, Ronald Hoffman, Wendy van Overveld, Joseph DeSimone, 2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia. Blood. ,vol. 96, pp. 2379- 2384 ,(2000) , 10.1182/BLOOD.V96.7.2379
Frank A. Ferrone, James Hofrichter, William A. Eaton, Kinetics of sickle hemoglobin polymerization. I. Studies using temperature-jump and laser photolysis techniques Journal of Molecular Biology. ,vol. 183, pp. 591- 610 ,(1985) , 10.1016/0022-2836(85)90174-3
Stefan Endres, Andreas Hacker, Eike Noack, Georg Kojda, Jochen Lehmann, NO-Donors, part 3: nitrooxyacylated thiosalicylates and salicylates - synthesis and biological activities(#). European Journal of Medicinal Chemistry. ,vol. 34, pp. 895- 901 ,(1999) , 10.1016/S0223-5234(99)00110-5
Claudia R. Morris, Frans A. Kuypers, Sandra Larkin, Nancy Sweeters, Julie Simon, Elliott P. Vichinsky, Lori A. Styles, Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease. British Journal of Haematology. ,vol. 111, pp. 498- 500 ,(2000) , 10.1111/J.1365-2141.2000.02403.X
Donald L. Pavia, Gary M. Lampman, George S. Kriz, Introduction to spectroscopy : a guide for students of organic chemistry Harcourt Brace College Publishers. ,(1996)
Frank A. Ferrone, James Hofrichter, William A. Eaton, Kinetics of sickle hemoglobin polymerization: II. A double nucleation mechanism Journal of Molecular Biology. ,vol. 183, pp. 611- 631 ,(1985) , 10.1016/0022-2836(85)90175-5