Collisional activation with random noise in ion trap mass spectrometry.

摘要: Random noise applied to the end caps of a quadrupole ion trap is shown be an effective means for collisional activation trapped ions independent mass/charge ratio and number ions. This technique compared contrasted with conventional single-frequency molecular N,N-dimethylaniline, protonated cocaine, anion 2,4,6-trinitrotoluene, doubly pronated neuromedin U-8. Collisional tends produce more extensive fragmentation than approach due fact that product are also kinetically excited in experiment. The efficiency experiment producing detectable relative ranges from being equivalent factor 3 less efficient. Furthermore, discrimination against low apparent data multiply charged biomolecules. Nevertheless, random provides very simple overcoming problems associated dependence on trap.