C1q PRECIPITINS IN THE SERA OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND OTHER HYPOCOMPLEMENTEMIC STATES: CHARACTERIZATION OF HIGH AND LOW MOLECULAR WEIGHT TYPES.

摘要: Precipitin reactions of C1q in gel diffusion proved useful detecting unknown complexes containing γ-globulin the sera patients with SLE. Using this method low molecular weight reactants also have been detected a number from SLE as well other diseases. Both circulating and unidentified are associated disease activity vivo complement depression. In some SLE, detectable by precipitation were closely cryoprecipitins an active nephritic process. Evidence is presented that both rheumatoid factors interact these interaction related to cryoprecipitation. The demonstration same cryoprecipitates renal glomerular deposits suggests special significance presence complexes.