The Three-Dimensional Structure at 6 A Resolution of a Human γG1 Immunoglobulin Molecule
作者： V. Raghupathy Sarma , Enid W. Silverton , David R. Davies , William D. Terry
DOI: 10.1016/S0021-9258(18)62192-1
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摘要: A three-dimensional electron density map has been calculated at 6 resolution for a human γG1 immunoglobulin molecule. X-ray diffraction data have collected the native protein crystals and three heavy atom derivatives prepared by soaking in p-chloromercuribenzenesulfonate, Hg(CN)2, PtCl6=. The is interpreted terms of four possible models, which T-shaped model favored. dimensions this are compared with those reported other physical chemical techniques molecules.
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sci-hub.st 参考文章(27)
Milton E. Noelken, Charles A. Nelson, C.E. Buckley, Charles Tanford, Gross Conformation of Rabbit 7 S γ-Immunoglobulin and Its Papain-cleaved Fragments Journal of Biological Chemistry. ,vol. 240, pp. 218- 224 ,(1965) , 10.1016/S0021-9258(18)97638-6
W. Bolton, Joyce M. Cox, M.F. Perutz, Structure and function of haemoglobin: IV. A three-dimensional Fourier synthesis of horse deoxyhaemoglobin at 5.5 Å resolution Journal of Molecular Biology. ,vol. 28, pp. 117- 150 ,(1967) , 10.1016/0022-2836(68)90294-5
Allen B. Edmundson, Mical K. Wood, Marianne Schiffer, Karl D. Hardman, Clinton F. Ainsworth, Kathryn R. Ely, Harold F. Deutsch, A Crystallographic Investigation of a Human IgG Immunoglobulin Journal of Biological Chemistry. ,vol. 245, pp. 2763- 2764 ,(1970) , 10.1016/S0021-9258(18)63134-5
D L Ross, B Jirgensons, The Far Ultraviolet Optical Rotatory Dispersion, Circular Dichroism, and Absorption Spectra of a Myeloma Immunoglobulin, Immunoglobulin G Journal of Biological Chemistry. ,vol. 243, pp. 2829- 2836 ,(1968) , 10.1016/S0021-9258(18)93447-2
L.W. Labaw, D.R. Davies, An Electron Microscopic Study of Human γG1 Immunoglobulin Crystals Journal of Biological Chemistry. ,vol. 246, pp. 3760- 3762 ,(1971) , 10.1016/S0021-9258(18)62193-3
Marianne Schiffer, Karl D. Hardman, Mical K. Wood, Allen B. Edmundson, Madonna E. Hook, Kathryn R. Ely, Harold F. Deutsch, A Preliminary Crystallographic Investigation of a Human l-Type Bence-Jones Protein Journal of Biological Chemistry. ,vol. 245, pp. 728- 730 ,(1970) , 10.1016/S0021-9258(18)63324-1
R R Porter, The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain Biochemical Journal. ,vol. 73, pp. 119- 127 ,(1959) , 10.1042/BJ0730119
G M Edelman, W E Gall, The Antibody Problem Annual Review of Biochemistry. ,vol. 38, pp. 415- 466 ,(1969) , 10.1146/ANNUREV.BI.38.070169.002215
B. W. Matthews, The extension of the isomorphous replacement method to include anomalous scattering measurements Acta Crystallographica. ,vol. 20, pp. 82- 86 ,(1966) , 10.1107/S0365110X6600015X
Daniel J. Goldstein, Richard L. Humphrey, Roberto J. Poljak, Human Fc fragment: crystallographic evidence for two equivalent subunits. Journal of Molecular Biology. ,vol. 35, pp. 247- 249 ,(1968) , 10.1016/S0022-2836(68)80053-1