Nanoethosomes for Topical Fungal Therapeutics

摘要: Topical treatment of fungal infections results in efficacious as the drug is intended to target site infection; systemic side effects are minimized and patient compliance improves significantly. The conventional topical antifungal formulations offer restricted delivery across skin resulting inefficient therapeutics non-targeted distribution drugs leading effects. needs accomplish two aspects: overcome stratum corneum barrier deposit targeted layers limit percutaneous absorption for fungicidal/fungistatic activity. To achieve this, various nanocarriers have been developed nanoethosomes hold promise. ethanolic vesicular nanosized system (classical ethosomes) has evolved variants form binary ethosomes, composite transethosomes, polymeric ethosomes. chapter provides an insight into occurrence therapy approaches infection, usefulness therapy, its variants, their applications agents.