Results of chemotherapy for cats with alimentary malignant lymphoma: 21 cases (1993-1997)

摘要: Objective To determine clinical and pathologic findings in cats with alimentary malignant lymphoma results of treatment a combination prednisone, L-asparaginase, vincristine, cyclophosphamide, doxorubicin, methotrexate. Design Retrospective study. Animals 21 lymphoma. Procedure Medical records were reviewed, information on signalment, history signs, previous treatments, laboratory tests, thoracic radiography, abdominal ultrasonography obtained. Results Test all negative for FeLV; 3 19 positive feline immunodeficiency virus. Thirteen tumors stage III, 7 IV, 1 was V. Diagnosis confirmed the basis microscopic examination histologic (n = 13) or cytologic (8) specimens. Immunophenotyping performed 13 tumors; 10 T-cell B-cell lymphomas. Overall median duration first remission 20 weeks. survival time 40 The only factor significantly associated whether had complete response following induction chemotherapy; time. Cats tolerated well; cat delay schedule because neutropenia. Clinical implications Use multidrug chemotherapeutic protocol that includes L-asparaginase doxorubicin minimal adverse effects prolonged times