Control of Pyridoxine Biosynthesis in Escherichia coli

摘要: Abstract Dempsey, Walter B. (University of Florida, Gainesville). Control pyridoxine biosynthesis in Escherichia coli J. Bacteriol. 90:431–437. 1965.—The total a culture exponentially growing was 3.6 × 10−10 moles per mg dry cells. One-fourth this present the medium, and at least 90% pyridoxal 5′-phosphate. Both pyridoxol pyridoxal, when initially 6 10−7m, substituted entirely for de novo synthesis pyridoxine. The other four forms group were ineffective concentration. Pyridoxine cultures E. immediately stopped by adding to medium final concentration 4 10−7m. Amino acid auxotrophs suspended minimal without required amino produced extracellular several hours an average rate 1.3 hr production threonine-starved threonine auxotroph not altered before starvation media containing 10−5m pyridoxol. form these starvations hydrolysis be detected bioassay used measurements. findings suggest that is controlled rapidly acting mechanism but repression.