Melatonin and psychiatry

作者: Andrew Miles , David R.S. Philbrick

DOI: 10.1016/0006-3223(88)90291-0

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摘要: Abstract The pineal methoxyindole melatonin remains the most widely studied of “pineal principles,” and in subhuman species, neuroendocrine status this hormone is now generally acknowledged. In humans, however, no definitive functional activity for has yet been convincingly demonstrated, despite description recent years marked changes metabolism several clinical categories. Currently, much interest focused on role that may play various psychiatric disorders, research represents one active areas current psychiatry research. Investigators field have encountered many technical practical difficulties, but advent impressively sensitive specific assay systems done to facilitate progress Present ideas suggest a positive involvement affective possible schizophrenic psychosis, potential other present review discusses etiological significance, diagnostic potential, utility psychiatry.

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