Local Drug Delivery Strategies for Gastric Cancer Treatment

摘要: Gastric cancer is associated with poor patient prognosis and, as a result, the leading cause of cancer-related death worldwide [1]. Systemic chemotherapy major treatment for locally advanced and metastatic gastric cancer, despite fact that satisfactory clinical outcomes have not been reached this approach. As such, exploring more effective modalities management necessary. Increasing evidence has shown most patients ultimately die from local recurrence or metastasis. To end, it reported positive peritoneal washing cytology negative prognostic factor in [2]. According to phase II study, 1-year survival rate after receiving modified FOLFOX-4 48 malignant ascites was 27.2% [3]. Many died metastasis, especially peritoneum Additionally, intraperitoneal proven improve rates well decrease dissemination [4, 5].