Comment on Salomon et al. Gestational Diabetes Mellitus Is Associated With Changes in the Concentration and Bioactivity of Placenta-Derived Exosomes in Maternal Circulation Across Gestation. Diabetes 2016;65:598–609

作者: Rucha Patil , Kanjaksha Ghosh , Shrimati Shetty

DOI: 10.2337/DB16-0295

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摘要: We read with interest the well-designed study by Salomon et al. (1) in which authors have shown a twofold increase placenta-derived exosomes (PdEs) women gestational diabetes mellitus (GDM) as compared those normal pregnancy at three points. They also bioactivity of these terms increased release proinflammatory cytokines from endothelial cells. We believe that, along PdEs, procoagulant microparticles (MPs) (total and placenta-derived) should …

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Carlos Salomon, Katherin Scholz-Romero, Suchismita Sarker, Emma Sweeney, Miharu Kobayashi, Paula Correa, Sherri Longo, Gregory Duncombe, Murray D. Mitchell, Gregory E. Rice, Sebastian E. Illanes, Gestational diabetes mellitus is associated with changes in the concentration and bioactivity of placenta-derived exosomes in maternal circulation across gestation Diabetes. ,vol. 65, pp. 598- 609 ,(2016) , 10.2337/DB15-0966