Molecular Mechanisms of Nuclear Receptor-Mediated Transcriptional Activation and Basal Repression
作者： Milan K. Bagchi
DOI: 10.1007/978-1-4612-1764-0_6
关键词:
摘要: The regulation of transcription eukaryotic protein-coding genes by RNA polymerase II occurs mostly during the initiation and early elongation steps. Initiation involves ordered assembly a set general factors into multiprotein complex at target promoter (Roeder 1991, Zawel Reinberg 1992, Conway 1993, Buratowski 1994). function is determined presence distinct DNA sequence elements in promoter. Sequence-specific bind to these control dramatically enhance or silence influencing preinitiation core (Tjian Maniatis A precise understanding mechanisms underlying gene regulatory events one major goals molecular biology.
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Riki Kurokawa, Mats Söderström, Andreas Hörlein, Shlomit Halachmi, Myles Brown, Michael G. Rosenfeld, Christopher K. Glass, Polarity-specific activities of retinoic acid receptors determined by a co-repressor Nature. ,vol. 377, pp. 451- 454 ,(1995) , 10.1038/377451A0
M.T. Bocquel, V. Kumar, C. Stricker, P. Chambon, H. Gronemeyer, The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific. Nucleic Acids Research. ,vol. 17, pp. 2581- 2595 ,(1989) , 10.1093/NAR/17.7.2581
S. Yeh, C. Chang, Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 5517- 5521 ,(1996) , 10.1073/PNAS.93.11.5517
Xavier Jacq, Christel Brou, Yves Lutz, Irwin Davidson, Pierre Chambon, Laszlo Tora, Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor Cell. ,vol. 79, pp. 107- 117 ,(1994) , 10.1016/0092-8674(94)90404-9
Stephen Buratowski, The basics of basal transcription by RNA polymerase II Cell. ,vol. 77, pp. 1- 3 ,(1994) , 10.1016/0092-8674(94)90226-7
Xun Zhang, M. Jeyakumar, Milan K. Bagchi, Ligand-dependent Cross-talk between Steroid and Thyroid Hormone Receptors Journal of Biological Chemistry. ,vol. 271, pp. 14825- 14833 ,(1996) , 10.1074/JBC.271.25.14825
Richard L. Wagner, James W. Apriletti, Mary E. McGrath, Brian L. West, John D. Baxter, Robert J. Fletterick, A structural role for hormone in the thyroid hormone receptor Nature. ,vol. 378, pp. 690- 697 ,(1995) , 10.1038/378690A0
Jeffrey D. Parvin, Phillip A. Sharp, DNA topology and a minimal set of basal factors for transcription by RNA polymerase II Cell. ,vol. 73, pp. 533- 540 ,(1993) , 10.1016/0092-8674(93)90140-L
S. J. Usala, J. B Menke, T.L. Watson, F. E. Wondisford, B. D. Weintraub, J. Bérard, W. E. C. Bradley, S. Ono, O. T. Mueller, B. B. Bercu, A homozygous deletion in the c-erbAβ thyroid hormone receptor gene in a patient with generalized thyroid hormone resistance: Isolation and characterization of the mutant receptor Molecular Endocrinology. ,vol. 5, pp. 327- 335 ,(1991) , 10.1210/MEND-5-3-327
O. Gandrillon, P. Jurdic, B. Pain, C. Desbois, J.J. Madjar, M.G. Moscovici, C. Moscovici, J. Samarut, Expression of the v-erbA product, an altered nuclear hormone receptor, is sufficient to transform erythrocytic cells in vitro Cell. ,vol. 58, pp. 115- 121 ,(1989) , 10.1016/0092-8674(89)90408-X