Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

作者: Claudia Bang , Sandor Batkai , Seema Dangwal , Shashi Kumar Gupta , Ariana Foinquinos

DOI: 10.1172/JCI70577

关键词:

摘要: … To investigate whether fibroblast-derived exosomes are crucially involved in this … exosomes released by cardiac fibroblasts are major components triggering cardiomyocyte hypertrophy…

参考文章(51)
Seán P. Barry, Paul A. Townsend, What causes a broken heart--molecular insights into heart failure. International Review of Cell and Molecular Biology. ,vol. 284, pp. 113- 179 ,(2010) , 10.1016/S1937-6448(10)84003-1
Clotilde Théry, Sebastian Amigorena, Graça Raposo, Aled Clayton, Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids Current protocols in pharmacology. ,vol. 30, ,(2006) , 10.1002/0471143030.CB0322S30
BERNARD SWYNGHEDAUW, Molecular Mechanisms of Myocardial Remodeling Physiological Reviews. ,vol. 79, pp. 215- 262 ,(1999) , 10.1152/PHYSREV.1999.79.1.215
Kefei Yuan, Ke Xie, John Fox, Huawei Zeng, Hongwei Gao, Canhua Huang, Min Wu, Decreased levels of miR-224 and the passenger strand of miR-221 increase MBD2, suppressing maspin and promoting colorectal tumor growth and metastasis in mice. Gastroenterology. ,vol. 145, pp. 853- 864 ,(2013) , 10.1053/J.GASTRO.2013.06.008
María Mittelbrunn, Cristina Gutiérrez-Vázquez, Carolina Villarroya-Beltri, Susana González, Fátima Sánchez-Cabo, Manuel Ángel González, Antonio Bernad, Francisco Sánchez-Madrid, Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells Nature Communications. ,vol. 2, pp. 282- 282 ,(2011) , 10.1038/NCOMMS1285
Chun Kwok Wong, Kin Mang Lau, Iris Hiu Shuen Chan, Shuiqing Hu, Yvonne Yi On Lam, Angela On Kei Choi, Christopher Wai Kei Lam, MicroRNA-21* regulates the prosurvival effect of GM-CSF on human eosinophils. Immunobiology. ,vol. 218, pp. 255- 262 ,(2013) , 10.1016/J.IMBIO.2012.05.019
Noriyuki Kioka, Kazumitsu Ueda, Teruo Amachi, Vinexin, CAP/ponsin, ArgBP2 : a Novel Adaptor Protein Family Regulating Cytoskeletal Organization and Signal Transduction Cell Structure and Function. ,vol. 27, pp. 1- 7 ,(2002) , 10.1247/CSF.27.1
Kai Wang, Shile Zhang, Jessica Weber, David Baxter, David J. Galas, Export of microRNAs and microRNA-protective protein by mammalian cells Nucleic Acids Research. ,vol. 38, pp. 7248- 7259 ,(2010) , 10.1093/NAR/GKQ601
Hongqiang Cheng, Kensuke Kimura, Angela K. Peter, Li Cui, Kunfu Ouyang, Tao Shen, Yujie Liu, Yusu Gu, Nancy D. Dalton, Sylvia M. Evans, Kirk U. Knowlton, Kirk L. Peterson, Ju Chen, Loss of Enigma Homolog Protein Results in Dilated Cardiomyopathy Circulation Research. ,vol. 107, pp. 348- 356 ,(2010) , 10.1161/CIRCRESAHA.110.218735