Genomics and Proteomics of Foodborne Microorganisms

摘要: Foods are teeming with microorganisms that may be innocuous, pathogenic threats, spoilage agents, or beneficial driving fermentations acting as biocontrol agents. This chapter outlines the basic concepts underlying genomics, proteomics, and associated technologies. With number of completely sequenced bacterial genomes increasing rapidly, one powerful approach to defining unique conserved gene content understanding how Lactobacillus plantarum evolved is comparative via an in silico analysis. The discipline functional genomics deals roles genes their appropriate organisms. utilizes proteomics demonstrate role SpaC mucin binding potentially its importance retention some lactobacilli gastrointestinal tract. principles behind DNA microarray technology make it very applicable many different uses include global expression While details Gad system were elucidated primarily by experiments Escherichia coli, bioinformatics have enabled researchers identify study effects these other contribution genome sequencing has greatly facilitated our pathogenicity Listeria monocytogenes. Differences between nonpathogenic species appear most strongly secretory proteome.