Analysis of prognostic risk factors in hepatic resection for metastatic colorectal carcinoma with special reference to the surgical margin

摘要: Background Liver resection for metastatic colorectal cancer has been established. Nevertheless, it is still controversial whether the surgical margin from tumour edge to cut surface of liver a significant prognostic factor in hepatic cancer. Methods To clarify risk factors metastasis, univariate and multivariate analyses were performed. Between April 1985 1995, 31 patients underwent curative cancer. The clinical pathological examined retrospectively. Results Overall 1-, 3- 5-year survival rates 92, 42 39 per cent respectively. Pathological study 16 resected specimens with solitary revealed vein invasion by cells two cases, portal three, microsatellite lesions biliary tract six cases. In measuring less than 4 cm diameter, one these was observed only nine whereas more seven (P<0.05). distance intrahepatic 10 mm. With analysis, size or an interval 6 months between resection, four gross tumours, bilobar involvement mm found be indicating poor prognosis. Cox's proportional hazards model identified diameter as (P<0·05). Conclusion treating liver, should because occult always located within tumour.