[Vitiligo: Clinical presentation and pathogenesis].

摘要: Background Vitiligo is a chronic skin disorder with depigmentation of circumscribed areas due to structural and functional damage melanocytes. Results There international consensus on the classification in nonsegmental segmental vitiligo. The influence vitiligo quality life significant influenced by ethnic sociocultural factors. new insight into genetic susceptibility, mechanisms targets autoimmune inflammation, altered morphology function melanocytes association other diseases, cancer therapy. Conclusions recognition associated disorders as important assessment changes life. New pathogenesis may have therapeutic consequences. relationship between immunotherapies patients metastatic melanoma warrants close clinical monitoring affected further scientific studies.