Saccharomyces boulardii stimulates sIgA production and the phagocytic system of gnotobiotic mice
作者： ACP Rodrigues , Denise Carmona Cara , SHGG Fretez , Fernando de Queiroz Cunha , EC Vieira
DOI: 10.1046/J.1365-2672.2000.01128.X
关键词:
摘要: The effect of Saccharomyces boulardii on the immune system was evaluated, comparing germ-free Swiss/NIH mice monoassociated with probiotic mice. colonized gut and survived gastrointestinal conditions. An increase in sIgA production, both total anti-S. boulardii, observed intestinal contents when compared controls. number Kupffer cells significantly higher than In S. boulardii-monoassociated mice, clearance Escherichia coli B41 TNF-alpha, IFN-gamma IL-12 serum levels were at earlier time points These results show that yeast modulates host responses. This may be interest for improving resistance to enteropathogenic bacterial infections.
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