Azetidine derivatives as g-protein coupled receptor (gpr119 ) agonists
作者： Chrystelle Marie Rasamison , William Gattrell , Matthew Colin Thor Fyfe
DOI:
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摘要: Compounds of formula (I) or pharmaceutically acceptable salts thereof, are agonists GPR119 and useful for the treatment diabetes as peripheral regulators satiety, e.g. obesity metabolic syndrome.
lens.org 参考文章(6)
Clive McCarthy, John James Woods, Darren Mark Le Grand, Clive Victor Walker, Azetidine derivatives as ccr-3 receptor antagonists ,(2003)
Mark R. Hellberg, James R. Shanklin, Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonvulsant agents ,(1991)
Jolanta Nowakowski, John Adams Lowe, Robert Alfred Volkmann, 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines ,(1998)
Chrystelle Marie Rasamison, Karen Lesley Schofield, Martin James Procter, Lisa Sarah Gardner, John King-Underwood, Matthew Colin Thor Fyfe, Gerard Hugh Thomas, Heterocyclic derivatives as gpcr receptor agonists ,(2004)
Catherine Rolland, Rafael Gozalbes, Eric Nicolaï, Marie-France Paugam, Laurent Coussy, Frédérique Barbosa, Dragos Horvath, Frédéric Revah, G-Protein-Coupled Receptor Affinity Prediction Based on the Use of a Profiling Dataset: QSAR Design, Synthesis, and Experimental Validation Journal of Medicinal Chemistry. ,vol. 48, pp. 6563- 6574 ,(2005) , 10.1021/JM0500673
Alan Daniel Brown, David Ellis, Andrew Antony Calabrese, Substituted triazole derivatives as oxytocin antagonists ,(2006)