Differential Expression of Estrogen Receptor-α and -β and Androgen Receptor in the Ovaries of Marmosets and Humans
作者： Philippa T.K. Saunders , Michael R. Millar , Karin Williams , Sheila Macpherson , Diana Harkiss
DOI: 10.1095/BIOLREPROD63.4.1098
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摘要: Abstract Estrogens and androgens are essential for the maturation of ovarian follicle normal fertility in female. We have used antibodies specific both forms estrogen receptor (alpha [ERα] beta [ERβ]) androgen (AR) to investigate pattern expression ovaries obtained from women a New World primate, Common marmoset (Callthrix jacchus). On Western blots, three directed against different peptides within human ERβ all recognized recombinant (h) but did not bind hERα. The protein was extracted ovary prostate ovary. In ovaries, detected nuclei granulosa cells sizes (both before after formation antrum), it also thecal cells, corpora lutea, surface epithelium, stroma. contrast, ERα preantral follicles, low/absent from...
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