Acetylcholine, Brain Activation, and Processing of Temporal Stimuli

摘要: In our daily lives we have to process sensory information at different speeds and in a specific manner. For example, if go for walk the park will need be aware of relatively slow pace changes environment, but as read this text characters that pass through fovea rapid succession. A child might her teacher starting or finishing discussion, only she is interested follow ongoing flow details. Because its anatomical characteristics well established role control global brain activity, neurotransmitter acetylcholine likely play large such temporal processing information. This work deals with two aspects time modulated stimuli, particularly it relates acetylcholine. Chapters 1 2 analyze acetylcholine's influence on an animal's ability discriminate between flashes light (chapter 1) trains sounds 2). Chapter 3 analyzes state, phenomenon tightly related cholinergic neural sounds, both thalamic cortical levels. Finally, chapter 4 undertakes problem mean neuronal firing rate measures representation. The thalamus differs dramatically states, analysis correlative activity must take into consideration. Our theoretical results can explain various current literature subject