Cardio-oncology: a new and developing sector of research and therapy in the field of cardiology

摘要: Cardio-oncology is a new field of interest in cardiology that focuses on the detection, monitoring, and treatment cardiovascular disease occurring as side effect chemotherapy radiotherapy. Both cancer modalities can cause cardiac dysfunction, major morbidity mortality oncologic population. It necessary to periodically monitor patients under treatment, especially those receiving anthracyclines trastuzumab (monoclonal antibody), using mainly 3D echocardiography calculate left ventricular ejection fraction estimate myocardial deformation. Additionally, measuring various biomarkers, such natriuretic peptides, could facilitate early identification appropriate response potential cardiotoxicity. In this regard, cardiological assessment before starting essential should be continued throughout, since dysfunction occur at any time, even several years after therapy onset. High-risk individuals, particular, receive detailed management plan designed collaboration between an oncology specialist. If heart failure develops, absence overt clinical symptoms, standard followed causal agent discontinued if possible. One important question whether when stop medication case reversal, completion treatment. Further cardio-oncology evolution lead deeper understanding adverse mechanisms effects causing failure, well development personalized regimens order limit