作者: Sellamuthu Kathiresan , Thangavel Anand , Subramanian Mugesh , Jamespandi Annaraj
DOI: 10.1016/J.JPHOTOBIOL.2015.04.016
关键词:
摘要: To evaluate the biological preference of synthetic small drugs towards DNA target, new metal based chemotherapeutic agents of Cu (II), Co (II), Ni (II) and Zn (II), 2, 4-diiodo-6-((pyridin-2-ylmethylimino) methyl) phenol (L) Schiff base complexes (1, 2, 3 & 4) having N, N, O donor system respectively were synthesized and thoroughly characterized. The IR results confirmed the tridentate binding of the ligand with metal centre during complexation and reflects the proposed structure. The density function theory calculations were also used …