DFT and Molecular Docking Studies on Biological Active Acridines: the Interaction with Bovine Serum Albumin
作者： Ali Mohammad Amani , Saeed Gholamzadeh , Mohammad Zarenezhad , Abdorrasoul Malekpour , Ehsan Javidnezhad
DOI: 10.18869/NRIP.JAMSAT.1.2.78
关键词:
摘要: Acridine derivatives, especially 1,8-dioxo-9-aryl-decahydroacridine represent significant scaffolds in medicinal chemistry. Given the biological properties of such products which are used drug development, they need to have appropriate carrier. Proteins generally as helpful tools delivery. Consequently, molecular docking between these compounds and bovine serum albumin (BSA) has been taken into account. Furthermore, order achieve better results, suggested optimized using Gaussian 03 software.
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sci-hub.st 参考文章(13)
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