Occurrence of Acute Oesophageal Necrosis (Black Oesophagus) in a Single Tertiary Centre

作者: Orlando Davide , Carabotti Marilia , Ruggeri Maurizio , Esposito Gianluca , Corleto Vito Domenico

DOI: 10.3390/JCM8101532

关键词:

摘要: Acute oesophageal necrosis (AON) is a rare condition characterised by the endoscopic finding of diffuse, circumferential, black mucosal pigmentation oesophagus, which typically stops at gastro-oesophageal junction. This observational study aimed to assess occurrence, clinical characteristics and outcomes AON in consecutive cohort single tertiary university centre. A retrospective analysis data upper gastrointestinal endoscopy (UGE) was carried out from 2008 2018. Out 25,970 UGE, 16 patients (0.06%) had AON; 75.0% were men with median age 75 years. Almost all underwent diagnosis during emergency UGE performed for bleeding, but one patient diagnosed elective persistent vomiting diarrhoea. All reported or more pre-existing comorbidities concomitant acute events. Two as first presentation Zollinger-Ellison syndrome (ZES). One developed an stenosis, another presented relapse AON. Mortality 50%, no died direct consequence cause bleeding mainly UGE. Our showed that ZES might manifest this critical presentation, endoscopists must be aware evidence.

参考文章(13)
Basil I Hirschowitz, Julie L Simmons, Lawrence F Johnson, Jean Mohnen, Risk factors for esophagitis in extreme acid hypersecretors with and without Zollinger-Ellison syndrome☆ Clinical Gastroenterology and Hepatology. ,vol. 2, pp. 220- 229 ,(2004) , 10.1016/S1542-3565(04)00009-6
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
Grigoriy E. Gurvits, Alexander Shapsis, Nancy Lau, Nicholas Gualtieri, James G. Robilotti, Acute esophageal necrosis: a rare syndrome Journal of Gastroenterology. ,vol. 42, pp. 29- 38 ,(2007) , 10.1007/S00535-006-1974-Z
M. Moretó, E. Ojembarrena, M. Zaballa, J. G. Tánago, S. Ibáǹez, Idiopathic acute esophageal necrosis: not necessarily a terminal event. Endoscopy. ,vol. 25, pp. 534- 538 ,(1993) , 10.1055/S-2007-1009121
K. Tanaka, H. Toyoda, Y. Hamada, M. Aoki, R. Kosaka, T. Noda, M. Katsurahara, M. Nakamura, K. Ninomiya, H. Inoue, I. Imoto, Y. Takei, A relapse case of acute necrotizing esophagitis Endoscopy. ,vol. 39, pp. E305- E305 ,(2007) , 10.1055/S-2007-966789
F. Augusto, V. Fernandes, M. Cremers, A. Oliveira, C. Lobato, A. Alves, C. Pinho, J. de Freitas, Acute necrotizing esophagitis: a large retrospective case series. Endoscopy. ,vol. 36, pp. 411- 415 ,(2004) , 10.1055/S-2004-814318
Brian E. Lacy, Arifa Toor, Steven P. Bensen, Richard I. Rothstein, Yogesh Maheshwari, Acute esophageal necrosis: report of two cases and a review of the literature Gastrointestinal Endoscopy. ,vol. 49, pp. 527- 532 ,(1999) , 10.1016/S0016-5107(99)70058-1
Grigoriy E. Gurvits, Karen Cherian, Mohamed Nafe Shami, Ravikiran Korabathina, Emad Mokhtar Abu El-Nader, Krishna Rayapudi, Frederick J. Gandolfo, Mohammad Alshumrany, Hiren Patel, Deepshikha N. Chowdhury, Aris Tsiakos, Black Esophagus: New Insights and Multicenter International Experience in 2014 Digestive Diseases and Sciences. ,vol. 60, pp. 444- 453 ,(2015) , 10.1007/S10620-014-3382-1
R. Ramos, J. Mascarenhas, P. Duarte, C. Vicente, C. Casteleiro, Acute esophageal necrosis: a retrospective case series Revista Espanola De Enfermedades Digestivas. ,vol. 100, pp. 583- 585 ,(2008) , 10.4321/S1130-01082008000900010
Grigoriy E Gurvits, Black esophagus: Acute esophageal necrosis syndrome World Journal of Gastroenterology. ,vol. 16, pp. 3219- 3225 ,(2010) , 10.3748/WJG.V16.I26.3219