Biofabrication of ecofriendly copper oxide nanoparticles using Ocimum americanum aqueous leaf extract: analysis of in vitro antibacterial, anticancer, and photocatalytic activities.

摘要: Nanotechnology tends to be a swiftly growing field of research that actively influences and inhibits the growth bacteria/cancer. Noble metal nanoparticles (NPs) such as silver, copper, gold have been used damage bacterial cancer over recent years; however, toxicity higher NPs concentrations remains major issue. The copper oxide (CuONPs) were therefore fabricated using simple green chemistry approach. Biofabricated CuONPs characterized UV-visible, FE-SEM with EDS, HR-TEM, FT-IR, XRD, Raman spectroscopy, XPS analysis. Formations observed by UV-visible absorbance peak at 360.74 nm. surface morphology showed spherical structure size (~ 68 nm). EDS spectrum has proved key signals (Cu) oxygen (O) components. FT-IR analysis, validate important functional biomolecules (O-H, C=C, C-H, C-O) are responsible for reduction stabilization CuONPs. monoclinic end-centered crystalline structures confirmed XRD planes. electrochemical states studied spectroscopy X-ray photoelectron. After successful preparation, examined their antibacterial, anticancer, photocatalytic activities. Green-fabricated promising antibacterial candidate against human pathogenic gram-negative bacteria Escherichia coli, Vibrio cholerae, Salmonella typhimurium, Klebsiella pneumoniae, Aeromonas hydrophila, Pseudomonas aeruginosa. demonstrated excellent anticancer activity A549 lung adenocarcinoma cell line. Furthermore, exhibited degradation azo dyes eosin yellow (EY), rhodamine 123 (Rh 123), methylene blue (MB). may an biomedical aid bacterial/cancer diseases dyes.