Phase equilibrium and bioproduction of the aroma compound 2-phenylethanol in a biphasic aqueous system
作者： Urszula Domańska , Marcin Okuniewski , Patrycja Okuniewska , Kamil Paduszyński , Tomasz Turowski
DOI: 10.1007/S00217-015-2421-2
关键词:
摘要: 2-Phenylethanol (PEA) is a very important natural aroma compound with roselike odor. The solid–liquid phase equilibrium (SLE) higher alkanols (decan-1-ol, hexadecan-1-ol, octadecan-1-ol and eicosan-1-ol), alkanes (eicosane) oleic acid has been determined at ambient pressure in order to explore their potential application for continuous product extraction during fermentation. A dynamic method was used over broad range of mole fractions temperatures from (246 338) K. Complete liquid miscibility simple liquidus curves were observed all binary (alkan-1-ol + PEA) systems. Liquid–liquid (LLE) the upper critical solution temperature case (eicosane, or acid + PEA) mixtures. Decan-1-ol chosen as best solvent PEA. influence on SLE up 700 MPa three different (303.15, 313.15 323.15) K. experimental data correlated non-random two-liquid equation, both LLE described average low root-mean-square deviation σ T = 1.25 K fraction x = 0.004 LLE. good agreement predictions group contribution model Mod. UNIFAC(Do) using published parameters. main aim this study determine biphasic situ removal T = 303.15 K. Two solvents, decan-1-ol acid, further tested yeast cell growth, found be biocompatible. well-known give better results than terms capability, biocompatibility overall performance bioprocess.
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