Age disparities in stage-specific colon cancer survival across seven countries: An International Cancer Benchmarking Partnership SURVMARK-2 population-based study.

摘要: We sought to understand the role of stage at diagnosis in observed age disparities colon cancer survival among people aged 50 99 years using population-based registry data from seven high-income countries: Australia, Canada, Denmark, Ireland, New Zealand, Norway and United Kingdom. used incidence for period 2010 2014. estimated 3-year net survival, as well conditional on surviving least 6 months 1 year after diagnosis, by country (categorised localised, regional or distant) flexible parametric excess hazard regression models. In all countries, increasing was associated with lower survival. For example, (95% confidence interval) 81% (80-82) 64 olds 58% (56-60) 85 74% (73-74) 39% (39-40) Kingdom, respectively. Those distant had largest difference between youngest oldest patients. Excess mortality patients localised cancers during first diagnosis. Older diagnosed (and some countries regional) who survived experienced same their younger counterparts. Further studies examining other prognostic clinical factors such comorbidities treatment, socioeconomic are warranted gain further understanding