Diabetes associated with male reproductive system damages: Onset of presentation, pathophysiological mechanisms and drug intervention

作者: Jing Wu , Guang-Yong Li , Qing Chang , Yu-Xiang Li , Jian-Qiang Yu

DOI: 10.1016/J.BIOPHA.2017.03.074

关键词:

摘要: Diabetes mellitus (DM) is a major health problem that affects patients' quality of life throughout the world due to its many complications. Reproductive dysfunction one secondary complications in both diabetic animals and human beings. Furthermore, DM has recently broken age barrier been heavily diagnosed children young persons reproductive age. In past few years, studies on male functions men experimental have published. It recognized sustained hyperglycemia, which impairs function men, at risk developing. harmfully multiple areas; these may include spermatogenesis, sperm maturation, fertility capability, penile erection, ejaculation. Traditional medicine folklore worldwide used numerous medicinal plants manage because bioactive phyto-constituents are affluent places. Unfortunately, exact reasons for not completely understood currently there no treatments specifically such lesions. The aim this review summarize current research findings functions, elaborate underlying mechanisms related diseases via vivo vitro studies, describe ameliorative effects or their products. provide systematic understanding lay theoretical foundation developing direction medicine.

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