Endocrine Aspects of Male Sexual Dysfunctions

作者: Jacques Buvat , Mario Maggi , Louis Gooren , Andre T Guay , Joel Kaufman

DOI: 10.1111/J.1743-6109.2010.01780.X

关键词:

摘要: ABSTRACT Introduction Endocrine disorders may adversely affect men's sexual function. Aim To provide recommendations based on best evidence for diagnosis and treatment of endocrine-related male dysfunctions. Methods The Aspects Male Sexual Dysfunctions Committee, including 11 members from eight countries four continents, collaborated with the subcommittee Standards Committee International Society Medicine. Medical literature was reviewed in detail, followed by extensive internal committee discussion over 2 years, then public presentation other experts before finalizing report. Main Outcome Measure Recommendations grading evidence-base medical interactive discussion. Results From animal studies, it is derived that testosterone modulates mechanisms involved erectile machinery, expression enzymes both initiate terminate erection. In addition, essential motivation. Whether these findings could be extrapolated to human erections unclear. Testosterone plays a broad role overall health. Recent studies have established strong associations between low metabolic cardiovascular imbalances. some decreased longevity; however, longitudinal do not support predictive value further events. article proposes standardized process dysfunctions, updating knowledge prostate safety. There no compelling causes cancer or its progression men without severe deficiency (TD). possible roles prolactin thyroid hormones are also examined. Conclusions Men dysfunction, hypoactive desire retarded ejaculation, as well those visceral obesity diseases, should screened TD treated. Prospective interventional required screening more conditions, considering correction preventive medicine much data suggests. Buvat J, Maggi M, Gooren L, Guay AT, Kaufman Morgentaler A, Schulman C, Tan HM, Torres LO, Yassin Zitzmann M. aspects

参考文章(444)
Dennis J. Krauss, Harvey A. Taub, Larry J. Lantinga, Milton H. Dunsky, Christine M. Kelly, Risks of Blood Volume Changes in Hypogonadal Men Treated with Testosterone Enanthate for Erectile Impotence The Journal of Urology. ,vol. 146, pp. 1566- 1570 ,(1991) , 10.1016/S0022-5347(17)38168-5
L Vignozzi, G Forti, G B Vannelli, S Filippi, F Ledda, M Maggi, Role of oxytocin in the ejaculatory process. Journal of Endocrinological Investigation. ,vol. 26, pp. 82- 86 ,(2003)
R S Swerdloff, C Wang, Androgen deficiency and aging in men. Western Journal of Medicine. ,vol. 159, pp. 579- 585 ,(1993)
David J Handelsman, Testosterone: use, misuse and abuse. The Medical Journal of Australia. ,vol. 185, pp. 436- 439 ,(2006) , 10.5694/J.1326-5377.2006.TB00642.X
Giuseppe Caminiti, Maurizio Volterrani, Ferdinando Iellamo, Giuseppe Marazzi, Rosalba Massaro, Marco Miceli, Caterina Mammi, Massimo Piepoli, Massimo Fini, Giuseppe M.C. Rosano, Effect of Long-Acting Testosterone Treatment on Functional Exercise Capacity, Skeletal Muscle Performance, Insulin Resistance, and Baroreflex Sensitivity in Elderly Patients With Chronic Heart Failure Journal of the American College of Cardiology. ,vol. 54, pp. 919- 927 ,(2009) , 10.1016/J.JACC.2009.04.078
Ratajczyk J, Lemaire A, Buvat J, [Role of hormones in sexual dysfunctions, homosexuality, transsexualism and deviant sexual behavior: diagnostic and therapeutic consequences]. Contraception Fertilite Sexualite. ,vol. 24, pp. 834- 846 ,(1996)
Kerrin Christiansen, Behavioural correlates of testosterone Testosterone. pp. 107- 142 ,(1998) , 10.1007/978-3-642-72185-4_3