“On-water” synthesis of novel trisubstituted 1,3-thiazoles via microwave-assisted catalyst-free domino reactions
作者： Shaik Karamthulla , Suman Pal , Md. Nasim Khan , Lokman H. Choudhury
DOI: 10.1039/C4RA06239F
关键词:
摘要: A clean, efficient and catalyst-free multicomponent domino reaction of arylglyoxals, cyclic 1,3-dicarbonyls thioamides in aqueous media under microwave conditions is reported. wide variety trisubstituted thiazoles can be synthesized good to very yields using this green protocol. The salient features methodology are: reaction, water as medium, short time, yields, use heating, no harmful by-products.
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