Many paths lead to discovery: analogical retrieval of cancer therapies

摘要: This paper addresses the issue of analogical inference, and its potential role as mediator new therapeutic discoveries, by using disjunction operators based on quantum connectives to combine many reasoning pathways into a single search expression. In it, we extend our previous work in which developed an approach retrieval Predication-based Semantic Indexing (PSI) model, encodes both concepts relationships between them high-dimensional vector space. As work, leverage ability PSI infer predicate connecting two example concepts, this case comprising known relationships. For example, given that drug x TREATS disease z, might pathway INTERACTS_WITH gene y ASSOCIATED_WITH use for drugs related another similar ways. biological systems tend be characterized networks relationships, evaluate quantum-inspired mediate inference across multiple relations, testing different approaches recover addition, introduce novel complex implementation PSI, Plate's Circular Holographic Reduced Representations, utilize all experiments addition binary have applied research.