Resected gastric cancer with D2 dissection: advances in adjuvant chemoradiotherapy and radiotherapy techniques.

摘要: Surgery is the main treatment option for locally advanced gastric cancer. D2 dissection has been recommended worldwide as standard lymphadenectomy resectable Furthermore, role of peri- or postoperative chemotherapy D2-dissected cancer established in both Western and European countries. It disputed whether adding radiotherapy to could further benefit those patients. Until recently, studies from Korea China may have made it clear. In North America, however, INT-0116 trial does not rule out that chemoradiotherapy effective patients with dissection, but ongoing CRITICS will, hopefully, clarify this. addition, literature published past decade supports theory improved techniques are likely accurately deliver radiation dose significantly reduce toxicity. Finally, status E2F-1 HER-2 be associated efficacy based on retrospective studies.