Venous thrombosis: risk factors and management.

摘要: During the past 2 decades, diagnostic and therapeutic approach to deep vein thrombosis (DVT) has greatly evolved. First, assessment of clinical probability gained wide acceptance. Second, novel noninvasive tools such as venous compression ultrasonography D-dimer measurement have become available, drastically reducing need for invasive phlebography. Third, new anticoagulant drugs, in particular low-molecular-weight heparins (LMWHs), available made DVT treatment a lot easier by allowing out-ofhospital management. Several algorithms, based on probability, ultrasonography, shown be safe management studies. In addition improvements algorithms treatment, therapy elastic stockings diminish prevalence postthrombotic syndrome been validated prospective The dilemma or no looking treating isolated calf with anticoagulants remains controversial issue, do optimal length intensity anticoagulation. near future, emergence several new, totally synthetic, orally active compounds, direct thrombin factor Xa inhibitors that are presently being tested studies, could profoundly change DVT.