Pancreas transplant results according to the technique of duct management: bladder versus enteric drainage.

摘要: Between July 1978 and February 1987, 177 pancreas transplants were performed. The 1-year patient graft survival rates for the first 100 up to October 1984 88% 27%, respectively. Since November 1984, duct drainage has been used 74 of 77 transplants, bladder (BD) in 36 enteric (ED) 38, with 89% 92%, respectively, 58% 42%. technical failure rate was similar both groups (31%). Immunosuppression antilymphocyte globulin, cyclosporine, azathioprine, prednisone. Most recipients nonuremic, without kidney 69% BD (n = 21) 42% ED 29). diagnosis rejection based on a decline urine amylase activity an increase plasma glucose alone group. For technically successful (TS) grafts, number episodes reversed per diagnosed 23 26 (18 patients) (88%) six 15 (14 (40%) (p less than 0.05). advantage monitoring is seen TS cases; cadaveric 90% 23) versus 47% 15) In segmental from living-related donors, 57% overall 18) cases 12), which identical cases. A disadvantage metabolic acidosis induced by chronic bicarbonate loss graft. Nevertheless, we conclude that preferred technique cadaver donors because ability monitor exocrine endocrine function continuously, thus leading early treatment episodes.