Ethanol and Fibrogenesis in the Liver
作者： E. G. Hahn , D. Schuppan
DOI: 10.1007/978-3-642-70048-4_7
关键词:
摘要: Rapid advances in connective tissue research offer a new perspective on molecular and cellular events alcoholic liver fibrosis, also provide quantitative approaches to monitoring its clinical course. Recently detected biological activities of distinct proteins the interstitial matrix may be fundamental importance for differentiated growth regeneration (Rojkind Kershenobich 1983), function micro- macrocirculation, hepatocytes, Kupffer cells severely disturbed by development excess tissue. The tridimensional pattern scarring acini plays pivotal role pathophysiology collateral circulation portal hypertension (Rappaport et al. many problems disease are closely linked hepatic fibrogenesis. This chapter will briefly review morphologic functional implications describe composition fibrotic pathogenesis, then discuss assessment fibrogenesis disease.
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