作者: L van Lee , A Geelen , J C Kiefte-de Jong , J C M Witteman , A Hofman
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摘要: BACKGROUND/OBJECTIVES: The Dutch guidelines for a healthy diet aim to reduce major chronic diseases. However, supporting evidence on their overall association with all-cause and cause-specific mortality is limited. Recently, the Healthy Diet-index (DHD-index) has been developed assess adherence these guidelines. was examine between DHD-index deaths from cardiovascular disease (CVD), coronary heart (CHD), stroke cancer. SUBJECTS/METHODS: We followed 3593 men women aged 55 years older enrolled in Rotterdam Study, populationbased prospective cohort study, baseline 1990–1993 2011. A validated 170-item food frequency questionnaire at used calculate score (maximum 90 points). Cox proportional hazard models were estimate ratios (HRs) adjusting age, sex, total energy intake, smoking educational level. RESULTS: During 20-year follow-up, 1831 (51%) reported. Mean 60.6 (s.d. 10.6). inversely associated (highest vs lowest quartile HR 0.77; 95% confidence interval (CI) 0.67, 0.89). Inverse but non-significant associations observed due CVD (HR 0.74; CI 0.55, 1.01), CHD 0.60; 0.34, 1.06) 0.67; 0.36, 1.22), whereas no cancer 0.99; 0.90, 1.11). CONCLUSIONS: higher level of dietary guidelines, as assessed DHD-index, lower risk mortality, probably an inverse causes death.