Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids
作者： Xiaoshan Shi , Yunchen Bi , Wei Yang , Xingdong Guo , Yan Jiang
DOI: 10.1038/NATURE11699
关键词:
摘要: Ionic protein–lipid interactions are critical for the structure and function of membrane receptors, ion channels, integrins and many other proteins 1 , 2 , 3 , 4 , 5 , 6 , 7 . However, the …
nature.com
harvard.edu
researchgate.net 
sci-hub.se 参考文章(31)
Felipe E Zilly, Nagaraj D Halemani, David Walrafen, Luis Spitta, Arne Schreiber, Reinhard Jahn, Thorsten Lang, Ca2+ induces clustering of membrane proteins in the plasma membrane via electrostatic interactions. The EMBO Journal. ,vol. 30, pp. 1209- 1220 ,(2011) , 10.1038/EMBOJ.2011.53
Rajat Varma, Gabriele Campi, Tadashi Yokosuka, Takashi Saito, Michael L. Dustin, T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster Immunity. ,vol. 25, pp. 117- 127 ,(2006) , 10.1016/J.IMMUNI.2006.04.010
Michael S. Kuhns, Mark M. Davis, The Safety on the TCR Trigger Cell. ,vol. 135, pp. 594- 596 ,(2008) , 10.1016/J.CELL.2008.10.033
Morgan Huse, Lawrence O. Klein, Andrew T. Girvin, Joycelyn M. Faraj, Qi-Jing Li, Michael S. Kuhns, Mark M. Davis, Spatial and Temporal Dynamics of T Cell Receptor Signaling with a Photoactivatable Agonist Immunity. ,vol. 27, pp. 76- 88 ,(2007) , 10.1016/J.IMMUNI.2007.05.017
Konstantina Nika, Cristiana Soldani, Mogjiborahman Salek, Wolfgang Paster, Adrian Gray, Ruth Etzensperger, Lars Fugger, Paolo Polzella, Vincenzo Cerundolo, Omer Dushek, Thomas Höfer, Antonella Viola, Oreste Acuto, Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Immunity. ,vol. 32, pp. 766- 777 ,(2010) , 10.1016/J.IMMUNI.2010.05.011
Lawrence J. Stern, Dikran Aivazian, Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition. Nature Structural & Molecular Biology. ,vol. 7, pp. 1023- 1026 ,(2000) , 10.1038/80930
M. I. Lioudyno, J. A. Kozak, A. Penna, O. Safrina, S. L. Zhang, D. Sen, J. Roos, K. A. Stauderman, M. D. Cahalan, Orai1 and STIM1 Move to the Immunological Synapse and Are Up-Regulated during T Cell Activation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 2011- 2016 ,(2008) , 10.1073/PNAS.0706122105
Alexander B. Sigalov, Dikran A. Aivazian, Vladimir N. Uversky, Lawrence J. Stern, Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits Biochemistry. ,vol. 45, pp. 15731- 15739 ,(2006) , 10.1021/BI061108F
I. G. Denisov, Y. V. Grinkova, A. A. Lazarides, S. G. Sligar, Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size. Journal of the American Chemical Society. ,vol. 126, pp. 3477- 3487 ,(2004) , 10.1021/JA0393574
Matthew R. Whorton, Roderick MacKinnon, Crystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and Sodium Cell. ,vol. 147, pp. 199- 208 ,(2011) , 10.1016/J.CELL.2011.07.046