Recent Advances in Mode of Action of Insecticides

摘要: The field of insecticide mode action has become so large that a review this length cannot hope to be comprehensive. I have therefore attempted clarify the current status only few unresolved or controversial problems and indicate certain possibilities for future research. omitted any discussion acetylcholinesterase-inhibitory organophos­ phate carbamate insecticides. Many other important topics novel concepts, including juvenile hormone (JR) mimics (44, 176), anti-JRs (21, 27, 156, 157, 175), cholinergic receptor agonists (98, 172), choline acetyl­ transferase inhibitors (164), I-phenylcarbamoyl-2-pyrazolines (73), gluta­ mate analogs (76, 122), antibodies as insecticides (142) are likewise not discussed. Recent accounts various aspects pyrethroids DDT can cited, effects on sodium potassium conductance changes (135-137), structure-activity relationships (55,83,84, 134, 138), inhibition calcium-independent ATPases (33, 45, 50). focused my group recent attempts locate their primary sites in vivo, relate neurotoxic calcium function. Other paths traced present aminergic theory formamidine action, mechanism synaptic facilitation by cyc10dienes y-BHC, question chitin synthetase benzoylphenyl urea It is assumed reader familiar with most basic principles neurophysiology.