The development and use of radiolabeled antitumor antibodies.

摘要: The use of radioactive tumor-localizing antibodies is developed historically, starting with the demonstration that can be radioiodinated without destroying antibody activity. Then, against normal organs were shown to contain which localize in organ. Subsequently, capable localizing tumors demonstrated, and these localized well enough permit their diagnostically by scanning for radioactivity therapeutically sufficient radioiodine. Various relevant problems are discussed.